Number of Credits
This course is a review of clinical and laboratory recognition of transfusion reactions and the responsibilities of both areas for prevention of and proper response to a suspected reaction.
Intended Audience: This program is designed as an educational and training tool for Clinical laboratory scientists, technologists and technicians. This course is also appropriate for clinical laboratory science students and pathology residents.
- Define transfusion reaction.
- Identify the risks of transfusions.
- Compare and contrast immediate hemolytic transfusion reactions and delayed hemolytic transfusion reactions.
- List and define the types of nonhemolytic transfusion reactions.
- List the laboratory findings associated with hemolytic and nonhemolytic transfusion reactions.
- Discuss the definition, pathophysiology, signs, symptoms, therapies, prevention, and clinical work-up of hemolytic and nonhemolytic transfusion reactions.
- List the antibodies associated with hemolytic transfusion reactions.
- List the steps and procedures to follow in a laboratory investigation of a transfusion reaction.
This course has been approved for P.A.C.E.® credit. There are no prerequisites for this course.
Adverse Effects of Blood Transfusions
Blood Component Transfusion Risks
Acute Immunologic Transfusion Reactions
- Acute Hemolytic Transfusion Reactions
- Febrile Nonhemolytic Transfusion Reactions
- Allergic Transfusion Reaction
- Transfusion-Related Acute Lung Injury (TRALI)
Delayed Immunologic Transfusion Reactions
- Delayed Hemolytic Transfusion Reactions
- Transfusion-Associated Graft Versus Host Disease (TA-GVHD)
- Post-Transfusion Purpura (PTP)
Acute Nonimmunologic Transfusion Reactions
- Bacterial Contamination
- Circulatory Overload
- Physical/Chemical Hemolysis
Delayed NonImmunologic Transfusion Reactions
Role of Medical Personnel Performing the Transfusion
Laboratory Investigation of a Transfusion Reaction.
Reporting Transfusion Reactions
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