One of the most widely performed laboratory tests is the prothrombin time (PT) test.  This test evaluates the functioning of the coagulation system and is also used to monitor patient oral anticoagulant therapy, such as warfarin.  Traditionally, the prothrombin time test has been reported out in seconds. However, due to variance in results from incomparable and inconsistent laboratory reporting methods and analyzers, there has been a push to report the International Normalized Ratio (INR) as the ‘gold standard’ for PT testing.  A key component of the INR calculation is the International Sensitivity Index (ISI). The purpose of this module is to provide a general overview of PT and INR calculation, reporting, and point-of-care implementation for laboratory and other medical personnel involved in patient testing.

This course has been approved for P.A.C.E.® credit. 

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